The biological data explosion of the 'omics' era requires fast access to many data types in rapidly growing data banks. The MRS software provides the tools to rapidly and reliably download, store, index, and query flat-file databanks. Data stored and indexed by MRS takes considerably less space on disk than the raw data, despite that these raw data are included. The MRS index information is part of the stored data. Therefore, public and private data can be combined by simple concatenation and thus without computational overheads....